[Effect of sex hormones on lipid peroxidation in the rat aorta]. / Perekisnoe okislenie lipidov v aorte krysy pri deistvii polovykh gormonov.

ABSTRACT

The effect of sex hormones on lipid peroxidation (LPO) in the wall of the aorta of male rats was studied in vivo and in vitro. Female sex hormones (17 beta-estradiol and progesterone) inhibited LPO in the aorta 17 beta-estradiol caused a maximum antioxidant effect at the beginning of its action, progester one during prolonged action. Testosterone had a marked prooxidant effect, activating lipid LPO in the aorta both in vivo and in vitro whatever its concentration and duration of incubation.