Studies on chemical constituents in root of Isatis indigotica / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the chemical constituents in the root of Isatis indigotica.</p><p><b>METHOD</b>The constituents root were separated through various chromatographic techniques and their structures were elucidated by means of physicochemical properties and the analysis of their spectral data.</p><p><b>RESULT</b>Eleven compounds were isolated and identified as (+) -isolariciresinol (1), lariciresinol (2), lariciresinol-9-O-beta-D-glucopyranoside (3), lariciresinol-4'-O-beta-D-glucopyranoside (4), lariciresinol-4,4'-bis-O-beta-D-glucopyranoside (5), 3-formylindole (6), 1-methoxy-3-indolecarbaldehyde (7), 1-methoxy-3-indoleacetonitrile (8), deoxyvasicinone (9), epigoitrin (10), adenosine (11).</p><p><b>CONCLUSION</b>Compounds 4-8 were isolated from I. indigotica for the first time.</p>