Optical coherence tomography for evaluation of neointimal proliferation after placement of a new drug eluting stent / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate neointimal proliferation following placement of a new drug-eluting stent (BUMA) by optical coherence tomography (OCT).</p><p><b>METHODS</b>Twenty-two patients with coronary artery disease were randomized into BUMA group (n=15) and Endeavor group (n=7) and underwent OCT imaging after 9 months of stent implantation.</p><p><b>RESULTS</b>The neointima hyperplasia (NIH) thickness in BUMA group were significantly smaller than that in endeavor group (0.220-/+0.140 mm vs 0.269-/+0.207 mm, P<0.001), and the uncovered Struts were significantly lower in BUMA group than in Endeavor group (5.65% vs 6.56%, P<0.0001). The luminal late loss in BUMA group was also significantly lower (34.87-/+11.50 vs 40.82-/+18.53, P=0.025).</p><p><b>CONCLUSION</b>BUMA stent is safe and effective for treatment of coronary artery disease.</p>