Amniotic fluid index measurement prior to the labor for prognosis of risk of Clifford syndrome

ABSTRACT

Infant with high risk of Clifford syndrome was predicted by mean of amniotic fluid index (AFI) measurement before labor. There is reliability by underwent ultrasound evaluation for AFI measurement with modified four quadrant techniques before labor. 287 pregnant women were involved in this study. Authors found that: A high negative linear regression correlation between AFI and gestational age 38 to 42 weeks. After 38 weeks the AFI appeared to decline gradually the mean AFI was 144+/-40 in 38 weeks and 88+/-35 in 42 weeks of gestational age. There is a high relationship between Clifford syndrome and AFI. The cut-off point AFI <=40 as a predictor for predicting the fetal outcome related Clifford syndrome with the positive predictive value = 90. The negative predictive value: 98.2%. The specificity predictive value 99% and the positive predictive value: 64%.