Clinical utility of circulating cell-free DNA in breast cancer / 中国肿瘤临床
Chinese Journal of Clinical Oncology
; (24): 261-264, 2015.
Article
en Zh
| WPRIM
| ID: wpr-461379
Biblioteca responsable:
WPRO
ABSTRACT
Circulating cell-free DNA (cfDNA), which is released by normal cells and cancer cells, is defined as extracellular DNA in the blood. The cfDNA levels in breast cancer patients are higher than those in healthy control donors. cfDNA also carries the features of tumor tissue, such as mutations, methylations, copy number changes, and loss of heterozygosis. cfDNA is a potential bio-marker in the diagnosis, management, and prognosis of breast cancer. In this review, the authors briefly describe the biological features of cfDNA, and discuss its clinical utility as a blood biomarker in quantitative and qualitative research.
Texto completo:
1
Banco de datos:
WPRIM
Tipo de estudio:
Qualitative_research
Idioma:
Zh
Año:
2015
Tipo del documento:
Article