Acute myeloid leukemia with NPM-MLF1 fusion gene: report of one case and review of literature / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma
; (12): 283-286, 2017.
Article
en Zh
| WPRIM
| ID: wpr-609814
Biblioteca responsable:
WPRO
ABSTRACT
Objective To investigate the characteristics of NPM-MLF1 fusion gene in acute myeloid leukemia (AML). Methods The data of one AML patient with NPM-MLF1 fusion gene was analyzed,and literatures were reviewed. Results A female patient was diagnosed as AML M6. In the course of the disease, 2 hematologic relapsed, and 2 recurrences were associated with NPM-MLF1 fusion gene positive. After inductive treatment, hematologic complete remission was achieved, and NPM-MLF1 fusion genes were all negative. Survival time surpassed 6 years when the chemotherapy was performed alone. Conclusion The incidence of NPM-MLF1 fusion gene in AML is low. It is necessary to collect more clinical data to judge whether an independent disease type or not.
Texto completo:
1
Banco de datos:
WPRIM
Tipo de estudio:
Prognostic_studies
Idioma:
Zh
Año:
2017
Tipo del documento:
Article