The structure, regulatory mechanism and biological function of the bacterial small RNA / 中华检验医学杂志

ABSTRACT

Non-coding small RNA in bacteria is usually not translated and comprise a size range between 50 and 500 nucleotides.With the development of high-density tiling arrays and RNA deep sequencing,studies of non-coding small RNAs attracts more and more attention,and meanwhile it is evident that non-coding small RNAs play a crucial role in many biological processes such as environmental sensing and stress adaptation, virulence and infectivity of intracellular bacteria, as well as development and metabolism.This article expound non-coding small RNA from following aspectsthe concept and structure, the characteristics and the classification,its regulatory mechanism and its effect on the biology of bacteria, thus providing a more comprehensive and clear understanding.