Iron overloading inhibits dentine mineralization
Acta odontol. latinoam
; 12(2): 75-81, 1999.
Article
em Es
|
LILACS-Express
| LILACS, BINACIS
| ID: biblio-1157620
Biblioteca responsável:
AR29.1
Localização: [{"text": "AR29.1"}]
ABSTRACT
The present study reveals the inhibitory effect of iron intoxication on the process of dentine mineralization. Wistar rats were injected intraperitoneally with iron dextran at 0.88 g/kg body weight per day for 10 days during the period of odontogenesis. An age-matched group was injected intraperitoneally with bisodium etidronate (EHBP) at 20 mg/kg body weight per day for 10 days. Another age-matched group was treated with similar amounts of saline intraperitoneally and considered as control. At the end of the experimental period the animals intoxicated with iron exhibited non-mineralized dentine and mineralized bone. The animals treated with EHBP showed non-mineralized dentine and bone. These findings would suggest the existence of different mineralization mechanisms for bone and dentine.
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Base de dados:
BINACIS
/
LILACS
Idioma:
Es
Ano de publicação:
1999
Tipo de documento:
Article