Fluorescent test accurately predicts leak of ischemic colon anastomosis in rats
Acta cir. bras
; 32(6): 440-448, June 2017. tab, graf
Article
em En
| LILACS
| ID: biblio-886209
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract Purpose:
To investigate if fluorescein fluorescent test can predict dehiscence in a model of ischemic colonic anastomosis in rats.Methods:
This experimental controlled trial randomly assigned 55 rats to four groups. Anastomoses were performed in non-ischemic colon segments (control group) and in ischemic colon segments measuring 1, 2 or 3 cm long (groups 1, 2 and 3, respectively). Fluorescein was injected and the tissues were examined under ultraviolet light. Seven days later, a second-look surgery was performed to check for the presence or absence of anastomosis dehiscence.Results:
Twenty-four rats presented anastomotic dehiscence during the second-look surgery. Reticular and nonfluorescent patterns were significantly associated with the occurrence of anastomotic dehiscence. Fluorescein fluorescence had a sensitivity of 95.8%, specificity of 89.2%, positive predictive value of 88.4%, negative predictive value of 96.2%, and accuracy of 92.3% to predict anastomotic dehiscence.Conclusion:
Fluorescein fluorescent test can accurately predict leak in a model of ischemic colonic anastomosis in rats.Palavras-chave
Texto completo:
1
Base de dados:
LILACS
Assunto principal:
Deiscência da Ferida Operatória
/
Anastomose Cirúrgica
/
Colo
/
Fluoresceína
/
Corantes Fluorescentes
/
Isquemia
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article