Capsiate treatment in liver surgeries may compromise its recovery
Acta cir. bras
; 33(5): 439-445, May 2018. graf
Article
em En
| LILACS
| ID: biblio-949344
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract Purpose:
To investigate the effects of capsiate treatment on hepatic hyperplasia in partially hepatectomized rats.Methods:
The animals were divided into a Capsiate group (CPH), a Capsiate Post-Partial Hepatectomy group (CPPH) and a Partial Hepatectomy Control group (PH). CPH and CPPH animals received 60 mg/kg/day Capsiate for 30 days. Next, the rats underwent partial hepatectomy. CPPH animals continued to receive treatment for 48 h after partial hepatectomy. Liver tissue and intracardiac blood samples were obtained 24 or 48 h after PH.Results:
Capsiate treatment interfered with hepatic parameters, reducing the number of mitoses and apoptosis and increasing blood ALT and alkaline phosphatase concentrations.Conclusion:
Capsiate treatment preceding hepatic surgery may compromise the initial period of postoperative recovery.Palavras-chave
Texto completo:
1
Base de dados:
LILACS
Assunto principal:
Capsaicina
/
Hepatectomia
/
Fígado
Limite:
Animals
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article