Multidisciplinary practice guidelines for the diagnosis, genetic counseling and treatment of pheochromocytomas and paragangliomas
Clin. transl. oncol. (Print)
; 23(10): 1995-2019, oct. 2021. ilus, tab
Article
em En
| IBECS
| ID: ibc-223371
Biblioteca responsável:
ES1.1
Localização: ES15.1 - BNCS
ABSTRACT
'Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors that arise from chromaffin cells of the adrenal medulla and the sympathetic/parasympathetic neural ganglia, respectively. The heterogeneity in its etiology makes PPGL diagnosis and treatment very complex. The aim of this article was to provide practical clinical guidelines for the diagnosis and treatment of PPGLs from a multidisciplinary perspective, with the involvement of the Spanish Societies of Endocrinology and Nutrition (SEEN), Medical Oncology (SEOM), Medical Radiology (SERAM), Nuclear Medicine and Molecular Imaging (SEMNIM), Otorhinolaryngology (SEORL), Pathology (SEAP), Radiation Oncology (SEOR), Surgery (AEC) and the Spanish National Cancer Research Center (CNIO). We will review the following topics epidemiology; anatomy, pathology and molecular pathways; clinical presentation; hereditary predisposition syndromes and genetic counseling and testing; diagnostic procedures, including biochemical testing and imaging studies; treatment including catecholamine blockade, surgery, radiotherapy and radiometabolic therapy, systemic therapy, local ablative therapy and supportive care. Finally, we will provide follow-up recommendations (AU)
Palavras-chave
Texto completo:
1
Base de dados:
IBECS
Assunto principal:
Paraganglioma
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Feocromocitoma
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Biomarcadores Tumorais
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Aconselhamento Genético
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article