Regulation of the renal proximal tubule second sodium pump by angiotensins
Braz. j. med. biol. res
; 34(8): 1079-1084, Aug. 2001. ilus
Article
em En
| LILACS
| ID: lil-290157
Biblioteca responsável:
BR1.1
RESUMO
For several years it was believed that angiotensin II (Ang II) alone mediated the effects of the renin-angiotensin system. However, it has been observed that other peptides of this system, such as angiotensin-(1-7) (Ang-(1-7)), present biological activity. The effect of Ang II and Ang-(1-7) on renal sodium excretion has been associated, at least in part, with modulation of proximal tubule sodium reabsorption. In the present review, we discuss the evidence for the involvement of Na+-ATPase, called the second sodium pump, as a target for the actions of these compounds in the regulation of proximal tubule sodium reabsorption
Texto completo:
1
Base de dados:
LILACS
Assunto principal:
Sódio
/
Angiotensina I
/
Angiotensina II
/
ATPase Trocadora de Sódio-Potássio
/
Espaço Extracelular
/
Túbulos Renais Proximais
Limite:
Animals
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article