Experimental infection parameters in Galea spixii (Rodentia: Caviidae) with Leishmania infantum chagasi
Mem. Inst. Oswaldo Cruz
; 103(6): 545-548, Sept. 2008. ilus, tab
Article
em En
| LILACS
| ID: lil-495729
Biblioteca responsável:
BR1.1
ABSTRACT
In order to better understand the epidemiological transmission network of leishmaniasis, an endemic disease in Northeast Brazil, we investigated the susceptibility of Spix yellow-toothed cavies (Galea spixii) to the Leishmania infantum chagasi parasite. Nine cavies were experimentally infected, separated into three groups and monitored at 30, 90 and 180 days, respectively. Amastigotes were identified in the spleen slides of two cavies killed 180 days after infection. Antibodies against the L. i. chagasi were identified in one of the cavies. This demonstrates that G. spixii is in fact capable of maintaining a stable infection by L. i. chagasi without alterations in biochemical and hematological parameters of the host and without perceivable micro and macroscopic lesions.
Palavras-chave
Texto completo:
1
Base de dados:
LILACS
Assunto principal:
Anticorpos Antiprotozoários
/
Leishmania infantum
/
Leishmaniose Visceral
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article