Extensively drug-resistant tuberculosis (
XDR-TB) is an emerging
health problem that threatens
tuberculosis (TB) control worldwide, since suitable
treatment for this
disease has not yet been found. We
report a case of
secondary pulmonary
XDR-TB in a 54-year-old,
HIV-negative
male from Goiânia,
Brazil. The
patient had long-standing
pulmonary tuberculosis (nine years) with extensive bilateral
lung damage and had been treated with multiple antituberculosis
drugs (
self-administered) before
XDR-TB diagnosis. The
strain of
Mycobacterium tuberculosis was resistant to R-
rifampicin, H-
isoniazid, E-
ethambutol, Eto-
ethionamide, Ofx-
ofloxacin, and Am-
amikacin. This
patient died with
multiple organ failure due to
sepsis secondary to
bacterial pneumonia.