Detection of Lsr2 gene of Mycobacterium leprae in nasal mucus
Braz. arch. biol. technol
; 55(3): 375-380, May-June 2012. tab
Article
em En
| LILACS
| ID: lil-640187
Biblioteca responsável:
BR1.1
ABSTRACT
In the present study, nasal mucus from patients with leprosy were analyzed by PCR using specific primers for Lsr2 gene of Mycobacterium leprae. The presence of Lsr2 gene in the nasal mucus was detected in 25.80% of patients with paucibacillari leprosy, and 23.07% of contacts. Despite the absence of clinical features in the contact individuals, it was possible to detect the presence of Lsr2 gene in the nasal mucus of these individuals. Therefore, PCR detection of M. leprae targeting Lsr2 gene using nasal mucus samples could contribute to early diagnosis of leprosy.
Texto completo:
1
Base de dados:
LILACS
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article