[Areas in Calabria with an elevated incidence of congenital hypothyroidism and iodine content of drinking water]. / Aree della Calabria con elevata incidenza di ipotiroidismo congenito e contenuto di iodio nelle acque potabili.
Ann Ist Super Sanita
; 34(3): 425-8, 1998.
Article
em It
| MEDLINE
| ID: mdl-10052189
ABSTRACT
The screening of 128,442 newborns, carried out in our laboratory from 1/1/1991 to 31/12/1996, detected 51 cases of congenital hypothyroidism (CH). Due to a 98% coverage, the accurate regional map of CH distribution has been obtained. Two rural and/or mountainous areas showed high incidence, 1/1145 (area A) and 1/1193 (area B), respectively. The incidence of the remaining region is 1/4621, whereas the mean regional incidence is 1/2518. In order to verify a relationship between CH incidence and iodine deficiency, we analyzed the iodine concentration in drinkable water from 148 localities. The high incidence of CH in the A and B areas corresponds with a high percentage of water samples with iodine concentration < 2 micrograms/l (92% and 85% respectively). In 15 coastal localities with low CH incidence, iodine concentration was between 7 and 80 micrograms/l. For populations of the A and B areas showing dietary iodine deficiency due to local product diet, we suggest the iodine prophylaxis as soon as possible.
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Base de dados:
MEDLINE
Assunto principal:
Abastecimento de Água
/
Hipotireoidismo Congênito
/
Iodo
Tipo de estudo:
Incidence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
/
Newborn
País como assunto:
Europa
Idioma:
It
Ano de publicação:
1998
Tipo de documento:
Article