Chromosomes, 11Q and cancer: a review.
J Pathol
; 187(1): 28-38, 1999 Jan.
Article
em En
| MEDLINE
| ID: mdl-10341704
ABSTRACT
This review aims at providing a general understanding of how the multiple cytogenetic aberrations in cancer cells arise and exemplifies this by considering the specific role of chromosome 11q loci in carcinogenesis. Section I provides a theoretical molecular and structural framework for understanding the cytogenetic aberrations described in cancer. Given this background, Section II describes advances in the identification and localization of cancer susceptibility genes on chromosome 11q, highlighting ongoing areas of investigation.
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Base de dados:
MEDLINE
Assunto principal:
Cromossomos Humanos Par 11
/
Transformação Celular Neoplásica
/
Aberrações Cromossômicas
Limite:
Humans
Idioma:
En
Ano de publicação:
1999
Tipo de documento:
Article