Serum apolipoprotein H and its relationship to lipids and other apolipoproteins in normal human men and women.
Blood Coagul Fibrinolysis
; 10(4): 197-200, 1999 Jun.
Article
em En
| MEDLINE
| ID: mdl-10390119
ABSTRACT
Apolipoprotein H (apo H), also known as beta-2-glycoprotein I, has recently become of considerable interest in the field of haemostasis. Because of the possible involvement of apo H in lipid pathways, we wished to test the hypothesis that the serum concentration of apo H was related to serum lipids and other apolipoproteins in normal individuals. One hundred and twenty-three healthy young subjects (67 women and 56 men) aged 22.7 +/- 0.70 years (mean +/- SD) were recruited. Serum level of apo H was higher in male subjects that in age-matched female subjects (167.6 +/- 47.5 mg/l versus 148.8 +/- 30.5 mg/l; P < 0.04). Serum levels of apo H were significantly correlated with serum concentration of cholesterol, but only in female subjects (r = 0.28, P < 0.02). No significant correlations were found between serum levels of apo H and triglycerides, high-density lipoprotein cholesterol, apo A1, apo B or lipoprotein (a) in either of the sexes.
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Base de dados:
MEDLINE
Assunto principal:
Glicoproteínas
/
Lipídeos
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
1999
Tipo de documento:
Article