Scavenger receptor BI and cholesterol trafficking.
Curr Opin Lipidol
; 10(4): 329-39, 1999 Aug.
Article
em En
| MEDLINE
| ID: mdl-10482136
ABSTRACT
Scavenger receptor BI (SR-BI) mediates the selective uptake of HDL cholesteryl ester into steroidogenic cells and the liver and is a major determinant of the plasma HDL concentration in the mouse. Recent studies indicate that SR-BI also alters the metabolism of apolipoprotein B-containing particles and influences the development of atherosclerosis in several animal models. These results and the similar pattern of SR-BI expression in humans emphasize that it is important to learn how this receptor influences lipoprotein metabolism and atherosclerosis in people.
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Base de dados:
MEDLINE
Assunto principal:
Receptores Imunológicos
/
Colesterol
/
Receptores de Lipoproteínas
/
Proteínas de Membrana
Tipo de estudo:
Etiology_studies
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
1999
Tipo de documento:
Article