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[Conformal radiotherapy of brain tumors]. / La radiothérapie conformationnelle des tumeurs cérébrales.
Haie-Meder, C; Beaudré, A; Breton, C; Biron, B; Cordova, A; Dubray, B; Mazeron, J J.
Afiliação
  • Haie-Meder C; Institut Gustave-Roussy, Villejuif, France.
Cancer Radiother ; 3(5): 407-13, 1999.
Article em Fr | MEDLINE | ID: mdl-10572510
Conformal irradiation of brain tumours is based on the three-dimensional reconstruction of the targeted volumes and at-risk organ images, the three-dimensional calculation of the dose distribution and a treatment device (immobilisation, beam energy, collimation, etc.) adapted to the high precision required by the procedure. Each step requires an appropriate methodology and a quality insurance program. Specific difficulties in brain tumour management are related to GTV and CTV definition depending upon the histological type, the quality of the surgical resection and the medical team. Clinical studies have reported dose escalation trials, mostly in high-grade gliomas and tumours at the base of the skull. Clinical data are now providing a better knowledge of the tolerance of normal tissues. As for small tumours, the implementation of beam intensity modulation is likely to narrow the gap between conformal and stereotaxic radiotherapy.
Assuntos
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Base de dados: MEDLINE Assunto principal: Planejamento da Radioterapia Assistida por Computador / Neoplasias Encefálicas / Neoplasias da Base do Crânio / Radioterapia Conformacional / Glioma Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: Fr Ano de publicação: 1999 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: Planejamento da Radioterapia Assistida por Computador / Neoplasias Encefálicas / Neoplasias da Base do Crânio / Radioterapia Conformacional / Glioma Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: Fr Ano de publicação: 1999 Tipo de documento: Article