Coexisting myelodysplasia and myeloproliferative features in a single clone containing 5q-, Ph and i(17q).
Leuk Res
; 23(10): 965-7, 1999 Oct.
Article
em En
| MEDLINE
| ID: mdl-10573144
ABSTRACT
A case with myelodysplasia in which a single clone contained both 5q- and Ph chromosomes at diagnosis is presented. The patient subsequently developed leukocytosis and at that time was found to have acquired an additional chromosomal abnormality, i(17)(q10). This case illustrates the role of three different genetic changes that impart different clinical characteristics, i.e. myelodysplastic as well as myeloproliferative changes, as part of a multistep leukemogenic process.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Síndromes Mielodisplásicas
/
Cromossomos Humanos Par 5
/
Cromossomo Filadélfia
/
Transtornos Mieloproliferativos
Limite:
Aged
/
Female
/
Humans
Idioma:
En
Ano de publicação:
1999
Tipo de documento:
Article