Canine osteosarcoma karyotypes from an original tumor, its metastasis, and tumor cells in tissue culture.
Transplant Proc
; 7(4): 485-93, 1975 Dec.
Article
em En
| MEDLINE
| ID: mdl-1060210
ABSTRACT
Radiation-induced osteosarcoma, its metastasis, and cells grown in tissue culture were karyotyped. Both hypodiploid and hyperdiploid stem lines were observed. The hypodiploid line contained 45-55 chromosomes with 10-15 abnormal metacentric and submetacentric chromosomes and one subtelocentric marker. The hyperdiploid line contained 90-105 chromosomes with 20-30 abnormal metacentric and submetacentric chromosomes with two subtelocentric markers. Karyotypic analysis can be used to monitor osteosarcomas maintained in tissue culture.
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Base de dados:
MEDLINE
Assunto principal:
Osteossarcoma
Limite:
Animals
Idioma:
En
Ano de publicação:
1975
Tipo de documento:
Article