Preventive immunisation could reduce the risk of meningococcal epidemics in the African meningitis belt.
Ann Trop Med Parasitol
; 93(5): 505-10, 1999 Jul.
Article
em En
| MEDLINE
| ID: mdl-10690246
ABSTRACT
Control of meningitis epidemics is based on early case detection followed by mass campaigns of immunisation. However, this strategy showed severe inadequacies during recent outbreaks in Africa. In Niamey, Niger, meningococcal vaccinations began in 1978 and detailed bacteriological and epidemiological surveillance of meningitis started in 1981. When vaccine coverage rates were higher than 50%, the prevalences of Neisseria meningitidis A meningitis were low in Niamey, although there was a concurrent epidemic in rural Niger. A massive outbreak of meningitis in Niamey in 1994-1995 followed a 6-year period during which the mean rate of vaccine coverage remained < 25%. The data indicate that, in the meningitis belt, preventive immunization should avoid a great number of deaths and be less expensive than mass immunisation campaigns performed after epidemics have begun.
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Base de dados:
MEDLINE
Assunto principal:
Vacinas Bacterianas
/
Surtos de Doenças
/
Imunização
/
Meningites Bacterianas
/
Neisseria meningitidis
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Evaluation_studies
/
Incidence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
País como assunto:
Africa
Idioma:
En
Ano de publicação:
1999
Tipo de documento:
Article