Sleep deprivation-induced reduction in cortical functional response to serial subtraction.
Neuroreport
; 10(18): 3745-8, 1999 Dec 16.
Article
em En
| MEDLINE
| ID: mdl-10716202
ABSTRACT
Thirteen normal volunteers were studied with fMRI during arithmetic performance after a normal night of sleep and following sleep deprivation (SD). Aims included determining whether the prefrontal cortex (PFC) and the parietal lobe arithmetic areas are vulnerable to the effects of SD. After a normal night of sleep, activation localized to the bilateral PFC, parietal lobes and premotor areas. Following SD, activity in these regions decreased markedly, especially in the PFC. Performance also dropped. Data from the serial subtraction task are consistent with Horne's PFC vulnerability hypothesis but, based on this and other studies, we suggest the localized, functional effects of SD in the brain may vary, in part, with the specific cognitive task.
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Base de dados:
MEDLINE
Assunto principal:
Privação do Sono
/
Encéfalo
/
Matemática
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Humans
Idioma:
En
Ano de publicação:
1999
Tipo de documento:
Article