Expression of hnRNP A2/B1 proteins in human cancer cell lines.
Int J Oncol
; 16(4): 763-7, 2000 Apr.
Article
em En
| MEDLINE
| ID: mdl-10717246
ABSTRACT
The overexpression of heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 is recently reported informative as a marker of lung cancer for early detection. To examine whether the expression of the proteins is specific for lung cancer, immunological analyses were performed both in lung and non-lung cancer cell lines. In immunostaining and Western blotting, the expression of A2/B1 was observed not only in the lung cancer cells but also in non-lung cancer cells. The expression of hnRNP A2/B1 is not specific for lung cancer and quantitative determination of A2/B1 is required to elucidate their significance in carcinogenesis.
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Base de dados:
MEDLINE
Assunto principal:
Ribonucleoproteínas
/
Ribonucleoproteínas Nucleares Heterogêneas Grupo A-B
/
Neoplasias
Tipo de estudo:
Screening_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2000
Tipo de documento:
Article