Design, synthesis and biological evaluation of 3-amino-3-phenylpropionamide derivatives as novel mu opioid receptor ligands.
Bioorg Med Chem Lett
; 10(6): 523-6, 2000 Mar 20.
Article
em En
| MEDLINE
| ID: mdl-10741545
ABSTRACT
3-Amino-3-phenylpropionamide derivatives were produced as small molecule mimics of the cyclic octapeptide octreotide from readily available imine 1. The compounds exhibit high affinity for the mu opioid receptor.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Benzilaminas
/
Receptores Opioides mu
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2000
Tipo de documento:
Article