Your browser doesn't support javascript.
loading
Abnormalities in CSF concentrations of ferritin and transferrin in restless legs syndrome.
Earley, C J; Connor, J R; Beard, J L; Malecki, E A; Epstein, D K; Allen, R P.
Afiliação
  • Earley CJ; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21224, USA.
Neurology ; 54(8): 1698-700, 2000 Apr 25.
Article em En | MEDLINE | ID: mdl-10762522
CSF and serum were obtained from 16 patients with idiopathic restless legs syndrome (RLS) and 8 age-matched healthy control subjects. Patients with RLS had lower CSF ferritin levels (1. 11 +/- 0.25 ng/mL versus 3.50 +/- 0.55 ng/mL; p = 0.0002) and higher CSF transferrin levels (26.4 +/- 5.1 mg/L versus 6.71 +/- 1.6 mg/L; p = 0.018) compared with control subjects. There was no difference in serum ferritin and transferrin levels between groups. The presence of reduced ferritin and elevated transferrin levels in CSF is indicative of low brain iron in patients with idiopathic RLS.
Assuntos
Buscar no Google
Base de dados: MEDLINE Assunto principal: Síndrome das Pernas Inquietas / Transferrina / Ferritinas Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Aged / Aged80 / Humans / Middle aged Idioma: En Ano de publicação: 2000 Tipo de documento: Article
Buscar no Google
Base de dados: MEDLINE Assunto principal: Síndrome das Pernas Inquietas / Transferrina / Ferritinas Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Aged / Aged80 / Humans / Middle aged Idioma: En Ano de publicação: 2000 Tipo de documento: Article