The bacA gene, which determines bacitracin susceptibility in Streptococcus pneumoniae and Staphylococcus aureus, is also required for virulence.

Chalker, Alison F; Ingraham, Karen A; Lunsford, R Dwayne; Bryant, Alexander P; Bryant, Joanna; Wallis, Nicola G; Broskey, John P; Pearson, Stewart C; Holmes, David J

Chalker, Alison F; Ingraham, Karen A; Lunsford, R Dwayne; Bryant, Alexander P; Bryant, Joanna; Wallis, Nicola G; Broskey, John P; Pearson, Stewart C; Holmes, David J.

Afiliação

Chalker AF; Anti-Infective Research (UP1345), SmithKline Beecham Pharmaceuticals, 1250 South Collegeville Road, PO Box 5089, Collegeville, PA19426-0989, USA1.
Ingraham KA; Anti-Infective Research (UP1345), SmithKline Beecham Pharmaceuticals, 1250 South Collegeville Road, PO Box 5089, Collegeville, PA19426-0989, USA1.
Lunsford RD; Anti-Infective Research (UP1345), SmithKline Beecham Pharmaceuticals, 1250 South Collegeville Road, PO Box 5089, Collegeville, PA19426-0989, USA1.
Bryant AP; Anti-Infective Research (UP1345), SmithKline Beecham Pharmaceuticals, 1250 South Collegeville Road, PO Box 5089, Collegeville, PA19426-0989, USA1.
Bryant J; Anti-Infective Research (UP1345), SmithKline Beecham Pharmaceuticals, 1250 South Collegeville Road, PO Box 5089, Collegeville, PA19426-0989, USA1.
Wallis NG; Anti-Infective Research (UP1345), SmithKline Beecham Pharmaceuticals, 1250 South Collegeville Road, PO Box 5089, Collegeville, PA19426-0989, USA1.
Broskey JP; Anti-Infective Research (UP1345), SmithKline Beecham Pharmaceuticals, 1250 South Collegeville Road, PO Box 5089, Collegeville, PA19426-0989, USA1.
Pearson SC; Anti-Infective Research (UP1345), SmithKline Beecham Pharmaceuticals, 1250 South Collegeville Road, PO Box 5089, Collegeville, PA19426-0989, USA1.
Holmes DJ; Anti-Infective Research (UP1345), SmithKline Beecham Pharmaceuticals, 1250 South Collegeville Road, PO Box 5089, Collegeville, PA19426-0989, USA1.

Microbiology (Reading) ; 146 ( Pt 7): 1547-1553, 2000 Jul.

Article em En | MEDLINE | ID: mdl-10878119

Assuntos

Proteínas de Bactérias/genética; Proteínas de Membrana/genética; Proteínas de Membrana Transportadoras; Staphylococcus aureus/genética; Streptococcus pneumoniae/genética; Sequência de Aminoácidos; Animais; Antibacterianos/farmacologia; Bacitracina/farmacologia; Proteínas de Bactérias/química; Proteínas de Bactérias/fisiologia; Modelos Animais de Doenças; Feminino; Masculino; Proteínas de Membrana/química; Proteínas de Membrana/fisiologia; Camundongos; Camundongos Endogâmicos CBA; Testes de Sensibilidade Microbiana; Dados de Sequência Molecular; Mutação; Fosfotransferases (Aceptor do Grupo Álcool)/genética; Fosfotransferases (Aceptor do Grupo Álcool)/fisiologia; Infecções Pneumocócicas/microbiologia; Homologia de Sequência de Aminoácidos; Staphylococcus aureus/efeitos dos fármacos; Staphylococcus aureus/patogenicidade; Streptococcus pneumoniae/efeitos dos fármacos; Streptococcus pneumoniae/patogenicidade; Virulência

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Staphylococcus aureus / Streptococcus pneumoniae / Proteínas de Bactérias / Proteínas de Membrana Limite: Animals Idioma: En Ano de publicação: 2000 Tipo de documento: Article

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