MHC antigen expression in human first trimester spinal cord with implications for clinical transplantation procedures.
J Neuroimmunol
; 111(1-2): 210-4, 2000 Nov 01.
Article
em En
| MEDLINE
| ID: mdl-11063840
ABSTRACT
We report human leukocyte antigen (HLA) class I expression in 5-17% and class II in 0-9% of first trimester human spinal cord cells. After 8 days in culture with gamma-interferon, >87% of the spinal cord cells expressed HLA class II. However, mixed cultures of adult human peripheral lymphocytes and immature human spinal cord cells, showed no induction of lymphocyte proliferation prior to or after gamma-interferon exposure in culture. In conclusion, we report non-immunogenic expression of HLA antigens in the human first trimester spinal cord.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Medula Espinal
/
Antígenos de Histocompatibilidade Classe I
/
Transplante de Tecido Fetal
Limite:
Humans
Idioma:
En
Ano de publicação:
2000
Tipo de documento:
Article