Transmission electron microscopy of the interface between bone and pseudowollastonite implant.
J Microsc
; 201(Pt 1): 33-43, 2001 Jan.
Article
em En
| MEDLINE
| ID: mdl-11136437
ABSTRACT
This paper reports on the structural morphology of the interface in vivo between implants composed of bioactive synthetic pseudowollastonite ceramic and bone in rat tibias. Thin sections of the interfaces were examined after 6 and 8 weeks of implantation period in a high resolution transmission electron microscope up to the lattice plane resolution level. The interfaces developed normal biological and chemical activities and remained reactive over the 8-week period. The regions showing direct bone tissue bonding to the implant contained nanocrystals of hydroxyapatite-like phase growing epitaxially across the interface in the [002] direction. The nanocrystals were also identified in the bone tissue formed in the interfacial area. The reactivity of the implant caused in the first instance formation of an amorphous woven type of bone, which transformed into a crystalline lamellar type containing collagen fibres. The Ca/P ratio of the interfacial region was found to be between 1.67 in the mature bone tissue formed about 5 microm from the interface, and 2.06 in the regions right at the interface.
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Base de dados:
MEDLINE
Assunto principal:
Osso e Ossos
/
Microscopia Eletrônica
/
Silicatos
/
Compostos de Cálcio
/
Substitutos Ósseos
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article