Quantitative expression analysis of the small conductance calcium-activated potassium channels, SK1, SK2 and SK3, in human brain.
Brain Res Mol Brain Res
; 85(1-2): 218-20, 2000 Dec 28.
Article
em En
| MEDLINE
| ID: mdl-11146124
ABSTRACT
Small conductance calcium-activated potassium (SK) channels are important in controlling neuronal excitability and three SK channels have been identified to date. In the present study, we report the first quantitative analysis of SK1, SK2 and SK3 expression in human brain using TaqMan RT-PCR on a range of human brain and peripheral tissue samples. SK1 expression is restricted to the brain whereas SK2 and SK3 are more widely expressed.
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Base de dados:
MEDLINE
Assunto principal:
Química Encefálica
/
Canais de Potássio
/
Reação em Cadeia da Polimerase Via Transcriptase Reversa
/
Canais de Potássio Cálcio-Ativados
Limite:
Humans
Idioma:
En
Ano de publicação:
2000
Tipo de documento:
Article