Canine models for human genetic neurodegenerative diseases.
Prog Neuropsychopharmacol Biol Psychiatry
; 24(5): 811-23, 2000 Jul.
Article
em En
| MEDLINE
| ID: mdl-11191715
ABSTRACT
1. Canine models of human neurodegenerative disorders are uncommon. However, the similarity between canines and humans in body sizes and physiology provides an exceptional opportunity to use these models to study human diseases. 2. The authors will present a review on the neurological deficits that have been observed in canine models of genetic neurodegenerative diseases, and summarize the current gene therapy treatments being developed for some of these conditions.
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Base de dados:
MEDLINE
Assunto principal:
Terapia Genética
/
Transtornos Heredodegenerativos do Sistema Nervoso
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
2000
Tipo de documento:
Article