Regional cerebral blood flow in patients suffering from post-traumatic stress disorder.
Neuropsychobiology
; 43(4): 260-4, 2001.
Article
em En
| MEDLINE
| ID: mdl-11340366
ABSTRACT
OBJECTIVE:
The aim of the study was to determine whether regional cerebral blood flow in survivors of torture suffering from post-traumatic stress disorder (PTSD) differed significantly from that in healthy controls.METHOD:
We examined the cerebral regional distribution of 99m-technetium-hexamethylpropyleneamineoxime (HMPAO) using single photon emission computed tomography (SPECT) in 8 patients and in 8 healthy controls. A semi-quantitative analysis was performed in which symmetrical regions of interest (ROI) were drawn in all subjects.RESULTS:
Regional blood flow was markedly more heterogeneous in patients suffering from PTSD than in healthy controls. The differences are significant.CONCLUSION:
Severe psychological trauma induced by torture can cause neurobiologic alterations that may contribute, even years after the original trauma, to a number of complaints commonly expressed by patients suffering from PTSD.
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Base de dados:
MEDLINE
Assunto principal:
Transtornos de Estresse Pós-Traumáticos
/
Circulação Cerebrovascular
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article