Leukocyte transendothelial migration: orchestrating the underlying molecular machinery.
Curr Opin Cell Biol
; 13(5): 569-77, 2001 Oct.
Article
em En
| MEDLINE
| ID: mdl-11544025
ABSTRACT
Transendothelial migration of leukocytes involves the spatiotemporal regulation of adhesion molecules, chemokines and cytoskeletal regulators. Recent results show that distinct steps of leukocyte transendothelial migration are regulated by sequential integrin activation and coordinated Rho family GTPase activity. Progress has been made in understanding how the dynamic regulation of these molecules translates into leukocyte transmigration.
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Base de dados:
MEDLINE
Assunto principal:
Endotélio Vascular
/
Quimiotaxia de Leucócito
Limite:
Humans
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article