Dextran reduces embolic signals after carotid endarterectomy.
Ann Neurol
; 50(4): 544-7, 2001 Oct.
Article
em En
| MEDLINE
| ID: mdl-11601508
ABSTRACT
One hundred fifty patients undergoing carotid endarterectomy were randomly assigned to receive intravenous 10% dextran 40 or placebo. Transcranial Doppler monitoring of the ipsilateral middle cerebral artery 0 to 1 hour postoperatively detected embolic signals in 57% of placebo and 42% of dextran patients, with overall embolic signal counts 46% less for dextran (p = 0.052). Two to 3 hours postoperatively, embolic signals were present in 45% of placebo and 27% of dextran patients, with embolic signal counts 64% less for dextran (p = 0.040). We conclude that dextran reduces embolic signals within 3 hours of CEA.
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Base de dados:
MEDLINE
Assunto principal:
Dextranos
/
Endarterectomia das Carótidas
/
Embolia Intracraniana
/
Anticoagulantes
Tipo de estudo:
Clinical_trials
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article