Somatostatin suppresses secretin and pancreatic exocrine secretion.
Science
; 190(4210): 163-5, 1975 Oct 10.
Article
em En
| MEDLINE
| ID: mdl-1166308
ABSTRACT
Somatostatin, a hypothalamic peptide, suppresses hydrochloric acid-stimulated release of secretin, pancreatic flow rate, and bicarbonate and protein secretion in fasted, conscious dogs. It also reduces nonstimulated pancreatic exocrine secretion but does not affect basal secretin concentrations. Suppression of HCl-stimulated secretin release is complete, whereas pancreatic flow rate and bicarbonate and protein secretions are only partially inhibited. The action of somatostatin is rapid in onset and quickly reversible.
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Base de dados:
MEDLINE
Assunto principal:
Pâncreas
/
Secretina
/
Somatostatina
Limite:
Animals
Idioma:
En
Ano de publicação:
1975
Tipo de documento:
Article