Report of a patient with a high level of parathyroid hormone-related peptide associated with malignant lymphoma involving multiple bony lesions.
Nephron
; 90(1): 103-5, 2002 Jan.
Article
em En
| MEDLINE
| ID: mdl-11744812
ABSTRACT
Hypercalcemia in malignant lymphoma is not common. Our case of malignant lymphoma with multiple bony lesions showed hypercalcemia (13 mg/dl) at the time of bone marrow relapse. The serum level of parathyroid hormone-related peptide increased to 142 pmol/l, which may be secreted by malignant lymphoma cells. The course of the patient was aggressive and she died from bone marrow relapse after 6 months of treatment including high-dose methotrexate, which caused acute nonoliguric renal failure. At autopsy there was extensive calcium deposition in the lungs, kidneys and pancreas and prominent tubular damage of kidneys.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Ósseas
/
Proteínas
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
/
Rim
Tipo de estudo:
Risk_factors_studies
Limite:
Child
/
Female
/
Humans
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article