Interaction of furazolidone with DNA.
Biochim Biophys Acta
; 402(2): 161-5, 1975 Aug 21.
Article
em En
| MEDLINE
| ID: mdl-1174533
ABSTRACT
DN forms a complex with furazolidone producing thereby a quenching and a bathochromic shift of the drug absorption pattern. The binding isotherm was a non-linear one indicating involvement of more than one binding process in the formation of the furazolidone - DNA complex. The furazolidone - DNA complex inhibited digestion of DNA by DNAase and stabilized DNA against thermal strand separation by a significant degree.
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Base de dados:
MEDLINE
Assunto principal:
DNA Bacteriano
/
Furazolidona
Idioma:
En
Ano de publicação:
1975
Tipo de documento:
Article