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On the detection of linkage in multiple data sets: a comparison of various statistical approaches.
Van Eerdewegh, P; Dowd, M; Dupuis, J; Falls, K; Hayward, B; Santangelo, S L.
Afiliação
  • Van Eerdewegh P; Genome Therapeutics Corporation, 100 Beaver Street, Waltham, MA 02453, USA.
Genet Epidemiol ; 21 Suppl 1: S67-72, 2001.
Article em En | MEDLINE | ID: mdl-11793760
We contrast the pooling of multiple data sets with the compound HLOD (HLOD-C) and the posterior probability of linkage (PPL), two approaches that have been shown to have more power in the presence of genetic heterogeneity. We also propose and evaluate several multipoint extensions.
Assuntos
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Base de dados: MEDLINE Assunto principal: Asma / Mapeamento Cromossômico Tipo de estudo: Diagnostic_studies Limite: Adult / Child / Female / Humans / Male Idioma: En Ano de publicação: 2001 Tipo de documento: Article
Buscar no Google
Base de dados: MEDLINE Assunto principal: Asma / Mapeamento Cromossômico Tipo de estudo: Diagnostic_studies Limite: Adult / Child / Female / Humans / Male Idioma: En Ano de publicação: 2001 Tipo de documento: Article