Tracing from the dorsal premammillary nucleus prosencephalic systems involved in the organization of innate fear responses.
Neurosci Biobehav Rev
; 25(7-8): 661-8, 2001 Dec.
Article
em En
| MEDLINE
| ID: mdl-11801291
ABSTRACT
The dorsal premammillary nucleus (PMd) is thought to play a critical role in the expression of fear responses to environmental threats. We have previously reported that, during an encounter with a predator, the PMd presents an impressive increase in Fos levels and cell body-specific chemical lesions therein virtually eliminated the expression of escape and freezing responses. Therefore, the PMd may be viewed as a strategic starting point to delineate prosencephalic circuits seemingly critical for the organization of innate fear responses. In the present review, we provide a comprehensive examination of the neural circuits putatively involved in influencing this hypothalamic site, and supplement this analysis with recent observations from our laboratory on the expression of Fos protein in the central nervous system of rats exposed to a live predator.
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Base de dados:
MEDLINE
Assunto principal:
Prosencéfalo
/
Corpos Mamilares
/
Medo
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article