Prophylactic surgery for women at high risk for breast cancer.
Clin Breast Cancer
; 1(2): 127-34; discussion 135, 2000 Jul.
Article
em En
| MEDLINE
| ID: mdl-11899651
ABSTRACT
Women at high risk for the development of breast cancer have several options open to them including increased cancer surveillance, prophylactic mastectomy and/or oophorectomy, and chemoprevention. We consider high-risk women to be those with known BRCA mutations or a strong family history characterized by multiple relatives with breast cancer, early age at diagnosis, and in some families, ovarian cancer. We present existing data regarding prophylactic surgery for these women. Essentially, a woman at high risk for breast cancer may choose to undergo bilateral prophylactic mastectomy, with or without reconstruction. For patients who have a known breast cancer, contralateral mastectomy is also an option. Finally, for women in families with a strong incidence of ovarian cancer, prophylactic oophorectomy can be considered.
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Base de dados:
MEDLINE
Assunto principal:
Prevenção Primária
/
Síndromes Neoplásicas Hereditárias
/
Neoplasias da Mama
/
Mastectomia
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
Idioma:
En
Ano de publicação:
2000
Tipo de documento:
Article