The crystal structure of catechol oxidase: new insight into the function of type-3 copper proteins.
Acc Chem Res
; 35(3): 183-91, 2002 Mar.
Article
em En
| MEDLINE
| ID: mdl-11900522
ABSTRACT
The crystal structure of catechol oxidase reveals new insight into the functional properties of the type-3 copper proteins. This class of proteins includes the closely related and better-known tyrosinase as well as hemocyanin, an oxygen transport protein. All these proteins have a dinuclear copper center, have similar spectroscopic behaviors, and show close evolutionary and functional relationships. Comparison between the 3D structures of catechol oxidase and hemocyanins reveals the structural reasons for the divergence in function.
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Base de dados:
MEDLINE
Assunto principal:
Catecol Oxidase
/
Cobre
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article