[Ultrastructural changes in the proper layer of the mucous membrane of the duodenum following general gamma-irradiation]. / Ul'trastrukturnye izmeneniia v sobstvennom sloe slizistoi obolochki dvenadtsatiperstnoi kishki pri obshchem gamma-obluchenii

The work has been performed on mature male Wistar rats which were irradiated in a "Gamma-Sell-220" apparatus in the dose of 1000 r, with thepower 42 r/sec. It has been shown that in early terms after irradiation (1-6 hours) slightly pronounced destructive changes were observed in cellular and fibrous structures of the stroma of theproper layer of the duodenum membrane in addition to pronounced exudative changes. Further, the latter increased and became maximum within 24 hours. The edema extends into the basal part of enterocytes and between the stroma cells giving rize to desorganization of all mucous membran elements. Seventy two hours after irradiation the destructive changes in cellular and fibrous structures of the mucous membrane layer proper became predominant. The authors make a conclusion that the changes in the stroma aggravate dysfunction of the epithelium injured by the irradiation energy.