Oxygen radicals in cardiovascular-renal disease.
Curr Opin Pharmacol
; 2(2): 121-5, 2002 Apr.
Article
em En
| MEDLINE
| ID: mdl-11950621
ABSTRACT
Oxidative stress is associated with diabetes mellitus and hypertension. Recent studies suggest that oxygen radicals contribute to the enhanced basal vascular tone, tubuloglomerular feedback, monocyte/macrophage infiltration and sensitivity of the vasculature and to the impaired endothelium-dependent relaxation in the diseased kidney. Pharmacological antioxidants can decrease oxidative stress, improve renal vascular function and decrease blood pressure in cardiovascular-renal disease.
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Base de dados:
MEDLINE
Assunto principal:
Espécies Reativas de Oxigênio
/
Nefropatias
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article