New cytotoxic analogues of annonaceous acetogenins.
Anticancer Drug Des
; 16(2-3): 109-17, 2001.
Article
em En
| MEDLINE
| ID: mdl-11962508
ABSTRACT
A series of new acetogenin analogues incorporating a central catechol moiety instead of the tetrahydrofuran ring(s) have been prepared and tested against L1210 leukemia cells. Although less potent than bullatacinone, which has the same terminal lactone, these compounds display interesting cell cycle effects.
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Base de dados:
MEDLINE
Assunto principal:
4-Butirolactona
/
Annonaceae
/
Álcoois Graxos
/
Antineoplásicos Fitogênicos
Limite:
Animals
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article