The influence of acridine dyes and caffeine on recovery from ultraviolet damage in Eudorina elegans.
Can J Microbiol
; 21(11): 1849-54, 1975 Nov.
Article
em En
| MEDLINE
| ID: mdl-1201521
ABSTRACT
Caffeine and the acridine dyes, acridine orange and acriflavine, were used to examine the repair potential in Eudorina elegans following ultraviolet irradiation. Acridines blocked photoreactivation primarily as a result of absorption of photoreactivating wavelengths, but acridines did not influence dark survival. Therefore, an acridine-sensitive excision-resynthesis-repair process is absent in Eudorina. Caffeine decreased both dark and light survival, the latter only after relatively high doses of ultraviolet light were used for inactivation. The caffeine-sensitive repair process appears to function most actively when the organisms are engaged in DNA synthesis, indicating that a postreplication-repair system exists in Eudorina. However, the data suggest that a repair system not associated with the DNA synthetic phases may also exist.
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Base de dados:
MEDLINE
Assunto principal:
Raios Ultravioleta
/
Acridinas
/
Cafeína
/
Reparo do DNA
/
Eucariotos
Idioma:
En
Ano de publicação:
1975
Tipo de documento:
Article