Diastereoselective formation of indanes from arylboronate esters catalyzed by rhodium(I) in aqueous media.
Org Lett
; 4(12): 2105-8, 2002 Jun 13.
Article
em En
| MEDLINE
| ID: mdl-12049529
ABSTRACT
[reaction see text] Arylboronate esters bearing a pendant Michael-acceptor alkene can add to norbornene and cyclize to give indane systems in yields ranging from 62% to 95% with high diastereomeric excess (>201). The reaction is performed in an organic/aqueous emulsion and catalyzed using [Rh(COD)Cl]2 with t-Bu-amphos chloride, a sterically bulky, electron-rich, water-soluble phosphine ligand.
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Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article