HLA-DRB1*15 and pediatric aplastic anemia.
Haematologica
; 87(7): 772-4, 2002 Jul.
Article
em En
| MEDLINE
| ID: mdl-12091130
ABSTRACT
We report a positive association between HLA-DRB1*15 (p= 0.0002) in Turkish patients with pediatric severe aplastic anemia (SAA) and a paradoxically favorable influence of the susceptibility marker on the clinical response to immunosuppressive therapy. These findings point to an immune mechanism mediated by DRB1*15 in SAA which confers responsiveness to treatment.
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Base de dados:
MEDLINE
Assunto principal:
Antígenos HLA-DR
/
Anemia Aplástica
Limite:
Child
/
Humans
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article