Assessment of the QoL in Italian menopausal women: comparison between HRT users and non-users.
Maturitas
; 42(4): 267-80, 2002 Aug 30.
Article
em En
| MEDLINE
| ID: mdl-12191849
ABSTRACT
OBJECTIVES:
The aim of this cross-sectional study was to describe QoL in a large sample of women attending menopause centres and compare untreated postmenopausal women and matched HRT users by employing the Women's Health Questionnaire (WHQ) and two generic instruments, the SF-36 and the EQ-5D.METHODS:
Overall, 2906 women were recruited by 64 menopause centres throughout Italy, of whom 2160 filled in the questionnaire (1093 on HRT and 1067 not on HRT; response rate 74%).RESULTS:
HRT users tended to be younger, healthier and with shorter menopause duration as opposed to non users, while no major socio-economic differences were present. At multivariate analysis, the presence of chronic diseases, low socio-economic status and living in Southern Italy represented the most important predictors of poor QoL. Furthermore, HRT users showed a lower probability of reporting problems in usual activities and pain/discomfort (EQ-5D), role limitations due to emotional problems (SF-36) and anxiety/fears (WHQ). HRT users also showed highly significant better outcomes in those areas that are more directly attributable to hormonal changes of mid age, namely vasomotor symptoms and sexual problems.CONCLUSIONS:
Although QoL is mainly influenced by socio-economic and cultural factors, HRT has the potential for improving not only symptoms, but also more general aspects of physical and psychological well-being of symptomatic postmenopausal women.
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Base de dados:
MEDLINE
Assunto principal:
Qualidade de Vida
/
Menopausa
/
Terapia de Reposição de Estrogênios
Tipo de estudo:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Middle aged
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article