Incidence of cancer among Nordic airline pilots over five decades: occupational cohort study.
BMJ
; 325(7364): 567, 2002 Sep 14.
Article
em En
| MEDLINE
| ID: mdl-12228131
ABSTRACT
OBJECTIVE:
To assess the incidence of cancer among male airline pilots in the Nordic countries, with special reference to risk related to cosmic radiation.DESIGN:
Retrospective cohort study, with follow up of cancer incidence through the national cancer registries.SETTING:
Denmark, Finland, Iceland, Norway, and Sweden.PARTICIPANTS:
10 032 male airline pilots, with an average follow up of 17 years. MAIN OUTCOMEMEASURES:
Standardised incidence ratios, with expected numbers based on national cancer incidence rates; dose-response analysis using Poisson regression.RESULTS:
466 cases of cancer were diagnosed compared with 456 expected. The only significantly increased standardised incidence ratios were for skin cancer melanoma 2.3 (95% confidence interval 1.7 to 3.0), non-melanoma 2.1 (1.7 to 2.8), basal cell carcinoma 2.5 (1.9 to 3.2). The relative risk of skin cancers increased with the estimated radiation dose. The relative risk of prostate cancer increased with increasing number of flight hours in long distance aircraft.CONCLUSIONS:
This study does not indicate a marked increase in cancer risk attributable to cosmic radiation, although some influence of cosmic radiation on skin cancer cannot be entirely excluded. The suggestion of an association between number of long distance flights (possibly related to circadian hormonal disturbances) and prostate cancer needs to be confirmed.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Aeronaves
/
Radiação Cósmica
/
Neoplasias Induzidas por Radiação
/
Doenças Profissionais
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Humans
/
Male
/
Middle aged
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article